Posaconazole 171228-49-2 Antibiotic
Totogi:T/T, L/C
Puna'oa:Saina
Taulaga Va'a:Beijing/Shanghai/Hangzhou
Gaosi gaosiga:20kg/masina
Poloaiga(MOQ):10g
Taimi muamua:3 Aso Galue
Tulaga teuina:Teu i totonu o se nofoaga malulu, matutu, potu vevela.
Mea fa'apipi'i:fagu
Tele le afifi:10g/vai
Fa'amatalaga saogalemu:E le o ni oloa matautia
Folasaga
Posaconazole o se vailaʻau faʻamaʻi faʻamaʻi triazole.
Posaconazole e faʻaaogaina e togafitia ai faʻamaʻi pipisi o Aspergillus ma Candida.E faʻaaogaina foi mo togafitiga o candidiasis oropharyngeal (OPC), e aofia ai le OPC refractory i itraconzaole ma / poʻo le fluconazole togafitiga.
E faʻaaogaina foʻi e togafitia ai faʻamaʻi pipisi e le Candida, Mucor, ma le Aspergillus ituaiga i tagata mamaʻi e le atoatoa le immunocompromised.
Fa'amatalaga (i totonu o le fale)
| Aitema | Fa'amatalaga |
| Fa'aaliga | Pa'epa'e pe toetoe a pa'epa'e, pa'u hygroscopic |
| Aitema | Fa'amatalaga |
| Fa'aaliga | Pa'epa'e po'o le pa'epa'e pa'epa'e tioata |
| Ta'amilosaga fa'apitoa | -28.0°~-34.0° |
| foliga tioata | E tatau ona tioata Ⅰ, ma tulimanu 2-theta o 14.4±0.2°,19.2±0.2°,21.7±0.2°,24.3±0.2°29.3±0.2° |
| Fa'ailoaga | IR, HPLC |
| Mea fa'atatau I | PO-R1 NMT 0.10% |
| PO-R2 NMT 0.10% | |
| PO-R3 NMT 0.10% | |
| PO-R4 NMT 0.10% | |
| PO-D3 & PO-D5 NMT 0.10% | |
| PO-D7 & PO-D10 NMT 0.10% | |
| O mea leaga uma e le'i fa'ailoaina NMT 0.10% | |
| Aofa'i le mama NMT 0.5% | |
| Mea fa'atatau Ⅱ | PO-E NMT 0.10% |
| PO-D1 NMT 0.10% | |
| PO-R5 NMT 0.10% | |
| Solivai totoe | Methanol NMT 3000ppm |
| Ethanol NMT 5000ppm | |
| Dichloromethane NMT 600ppm | |
| Tetrahydrofuran NMT 720ppm | |
| N, N-dimethyl formamide NMT 880ppm | |
| Triethylamine NMT 100ppm | |
| Dimethy sulfoxide NMT 5000ppm | |
| Vai | NMT 2.0% |
| Toega ile mu | NMT 0.1% |
| Metala mamafa | NMT 10ppm |
| tapulaa microbial | Aerobic NMT 1000cfu/g Aofa'i fefete ma limu NMT 100cfu/g E.coli e tatau ona toesea |
| Su'ega | 98.0% -102.0% (i luga ole fa'avae) |
| 98.0% -102.0% (i luga ole anhydrous ma solvents free faavae) |
