Orlistat 96829-58-2 Antiobesity Diet faaopoopo
Totogi:T/T, L/C
Puna'oa:Saina
Taulaga Va'a:Beijing/Shanghai/Hangzhou
Gaosi gaosiga:800kg/masina
Poloaiga(MOQ):25kg
Taimi muamua:3 Aso Galue
Tulaga teuina:Teu i totonu o se nofoaga malulu, matutu, potu vevela.
Mea fa'apipi'i:talipalau
Tele le afifi:25kg/tapa
Fa'amatalaga saogalemu:E le o ni oloa matautia
Folasaga
Orlistat o se faʻataʻitaʻiga lipase lipase faʻamaʻi umi ma malosi.E pa'epa'e pe toeititi pa'epa'e pauta i le vevela o le potu, e le mafai ona solu ile vai, solu ile chloroform, ma faigofie ona solu ile ethanol.Na te fa'agataina le enzyme e ala i le fa'atupuina o so'o fa'atasi ma nofoaga fa'agaoioi o serine o le gastric lipase ma le pancreatic lipase i le manava ma le to'oto'o laiti.
Orlistat o se ituaiga lipase inhibitor pa'u mamafa fualaau.O se faʻamaʻi faʻamamaina o le lipstatin, lea e mafai ona faʻaitiitia ai le faʻaogaina o gaʻo meaʻai ma faʻaitiitia le mamafa.O lenei oloa e malosi ma filifili le taofiofia o le gastric lipase ma le pancreatic lipase, e leai sona aafiaga i isi enzymes digestive (amylase, trypsin, chymotrypsin) ma le phospholipase, ma e le afaina ai le faʻaogaina o gaʻo, polotini ma phospholipids.E le faʻaaogaina le enzyme e masani lava e ala i le fusifusia faʻatasi ma serine toega i nofoaga gaʻo o le gastric lipase ma le pancreatic lipase i totonu o le gastrointestinal tract, faʻalavelaveina le hydrolysis o le triacylglycerol, faʻaitiitia le faʻaaogaina o le monoglyceride ma le gaʻo gaʻo saoloto, ma faʻapea ona pulea le mamafa o le tino.O le vailaʻau e le faʻafefeina e le gastrointestinal tract, ma o le faʻasaina o le lipase e mafai ona toe faʻafoʻi.
O lenei oloa e iai foʻi le galuega o le faʻatonutonuina o lipids toto.E mafai ona faʻaititia le triglyceride ma le maualalo o le lipoprotein cholesterol i le serum o tagata mamaʻi ma faʻateleina le fua o le lipoprotein maualuga i le lipoprotein maualalo.
Pe a tuʻufaʻatasia le orlistat ma se meaʻai maualalo kalori, e talafeagai mo togafitiga umi o tagata lapopoa ma le mamafa, e aofia ai i latou na atiaʻe faʻalavelave faʻalavelave faʻalavelave.E iai taimi umi e pulea ai le mamafa e pei o le pa'u o le mamafa, tausiga o le mamafa ma le puipuia o le toe fa'afo'i.O lo'o fa'aalia manino e le falema'i o le fa'atonuga o le mamafa e aoga tele mo le fa'aaogaina umi pe a fa'atasi ma mea'ai pe a mae'a le tasi itula o taumafataga.
Orlistat e mafai ona faʻaitiitia ai le faʻalavelave faʻafuaseʻi o aʻafiaga e aʻafia ai le gaʻo ma isi faʻamaʻi faʻamaʻi, e aofia ai le hypercholesterolemia, maʻisuka ituaiga II, faʻaletonu le faʻapalepale o le kulukose, hyperinsulinemia, toto maualuga, ma faʻaitiitia le gaʻo i totonu o totoga.
Fa'amatalaga (USP42)
| Aitema | Fa'amatalaga |
| Fa'ailoaga | HPLC, IR |
| Fa'ailo fa'apitoa | -48.0°~-51.0° |
| vai vai | ≤0.2% |
| Mea fa'atatau I | Orlistat feso'ota'iga fa'atasi A ≤0.2% |
| Mea e fesootai i ai II | Orlistat fa'afeso'ota'i fa'atasi B ≤0.05% |
| Mea e fesoota'i III
| Formylleucine ≤0.2% |
| Orlistat feso'ota'i fa'atasi C ≤0.05% | |
| Orlistat mama mama epimer ≤0.2% | |
| D-Leucine orlistat ≤0.2% | |
| Ta'ito'atasi le fa'ailoaina le mama ≤0.1% | |
| Mea e feso'ota'i IV | Orlistat fa'afeso'ota'i fa'atasi D ≤0.2% |
| Orlistat mama mama amide ≤0.1% | |
| Mea fa'atatau V | Orlistat e feso'ota'i fa'atasi E ≤0.2% |
| Aofa'iga o mea leaga (I i le V) | ≤1.0% |
| Solivai totoe | Methanol ≤0.3% |
| EtOAc ≤0.5% | |
| n-Heptane ≤0.5% | |
| Toega ile mu | ≤0.1% |
| Uamea mamafa e pei o le Pb | ≤20ppm |
| Suʻega e le HPLC | 98.0% ~ 101.5% (i luga o le anhydrous, fa'avae leai se soli) |
